The Orbital Transfer Vehicle will be controlled remotely like any other drone aircraft. Command and Control (CnC) will look no different than the trenches at Mission Control Center at NASA. There will, however, be one glaring difference: the existence of what looks to be a static simulator of the OTV cockpit.
The layout has two pilots side–by–side, with a glass cockpit and and what look like large screen TVs in the place of windows in front and on the sides of the pilots. The crew operates the OTV spacecraft remotely, from undock to redocking.
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